Doctorant-e FNS en Sciences de La vie (PhD Student)

Lausanne
09.12.2020 | Position with re­spon­si­bil­i­ties | 100%

Doctorant-e FNS en Sciences de La vie (PhD Student)

Doctorant-e FNS en Sciences de La vie (PhD Student)

Département DMLP - Dpt de médecine de laboratoire et pathologieCode emploi Assistant Doctorant - 0131Niveau Hors DECFODate d'entrée souhaitée 01-02-2021Type de contrat CDDDate de fin de contrat 31-01-2022Catégorie professionnelle Médico-techniquesLieu LausanneTaux d'activité 80% - 100% Date de début de publication 09-12-2020 Date de fin de postulation 31-01-2021 Référence 06440-MT-210-2020 Documents

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Contexte

The Lausanne University Hospital (CHUV) is one of five Swiss university hospitals. Through its collaboration with the Faculty of Biology and Medicine of the University of Lausanne and the EPFL, CHUV plays a leading role in the areas of medical care, medical research and training.

The Haemostasis and Platelet Research Laboratory belongs to the Service and Central Laboratory of Hematology of the CHUV and the University of Lausanne.

The goals of our lab are:

  • To develop new tools to investigate and dissect signaling mechanisms underlying and modulating procoagulant collagen-and-thrombin (COAT) activated platelets generation (e.g., cytoplasmic ion fluxes and protein phosphorylation).

  • To study the role and clinical impact of procoagulant COAT platelets in hematological diseases, such as paroxysmal nocturnal hemoglobinuria, myeloproliferative neoplasms, heparin-induced thrombocytopenia (HIT), and in transfusion medicine.

  • To evaluate diagnostic utility of thrombin generation assays in following clinical conditions: rare bleeding disorders, new direct oral anticoagulants (DOAC), and patients with liver disease.

  • To investigated mechanistic, diagnostic, and therapeutic aspects of HIT.

Mission

  • You will carry out a research project in the field of platelet biology / physiology and you will be involved in the research activity focusing on the characterization of procoagulant COAT platelets.

  • You will contribute to develop new methods to study procoagulant platelets with flow cytometry and microfluidic flow chamber model, using fluorescence microscopy.

  • You will conduct experiments, including preparation of substrates, isolation of platelets from blood, fluorescent staining procedures, flow cytometry, and fluorescence microscopy.

  • You will contribute to the management of the project, including purchase of supplies and general laboratory maintenance, literature search, experimental planning, synthesis and interpretation of your results.

  • You will write research grants, reports, and manuscripts for scientific publications.

  • You will present your research work to regular lab meetings, national and international congress.

Profil

  • You graduated from a Master in life sciences, biology or equivalent

  • You have strong interest for research

  • You are nimble-minded and you have a sense of collaboration, creativity, good analytical and synthesis capacities

  • You have good command of English, both spoken and written

  • You are familiar with the general basic techniques in a laboratory

  • You have skills in flow cytometry and protein analysis

  • Knowledge in fluorescence microscopy are an asset

  • You are adaptable to irregular schedules.

Nous offrons

If you become an employee at the Centre Hospitalier Universitaire Vaudois, we will offer you the following :

  • High social benefits

  • Regular salary progression according to job responsibilities

  • Three days of training per year

  • 25 working days of vacation per year

  • Very good restaurants with preferential rates.

Contact et envoi de candidature

Contact for information on the function :Prof. Lorenzo Alberio, Tél. 079 556 14 25

As our applications are processed electronically, would you please apply exclusively by internet, with the « POSTULER » button, at the bottom of the ad. If for any technical reason, you are not able to do it, we invite you to contact our recruitment team, which will assist you (contact : 021.314.85.70).

The CHUV applies the highest quality requirements as part of its recruitment process. In addition, mindful to promote the diversity of our employees we are attentive to the different life courses and strive to ensure equal treatment and avoid any discrimination. We are looking forward to receiving your application.

We thank in advance the employment agencies to take note that applications inserted by them directly on our recruitment platform are not accepted and cannot be billed. Thank you for your understanding.