Roche Postdoctoral Fellow (RPF) in Podocyte Rejuvenation

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The Position

As a Postdoctoral Fellow in the Department of CMI2O (cardio-metabolic, immunology, infectious diseases and ophthalmology), you will focus on an ambitious exploratory research project aiming at establishing an in vitro platform for monitoring human podocyte function in health and disease states, amenable for phenotypic screening and deep knowledge generation. This work directly contributes to Roche’s goal to preserve renal function in patients with Chronic Kidney Disease (CKD).

The University of Guelph (Ontario, Canada) is Roche’s academic partner for this Postdoctoral Fellowship. The partnership with Academia will provide further insights into fundamental podocyte biology and signaling pathways and will provide access to complementary research tools including mouse models.

In this position you will:

• Ensure the design, development, execution and implementation of scientific research in collaboration with a multidisciplinary research team.

• Investigate the feasibility of applying a wide variety of scientific principles and theories to potential development of novel therapies for patients with diabetic kidney diseases.

• Maintain substantial knowledge and know-how of state-of-the-art principles and technologies.

• Analyze data using appropriate statistical methods and present data in a professional format suitable for external publication.

• Work closely with the Roche Institute of Human Biology (IHB), an organization within pRED whose goal is to harness and advance the use of human model systems in drug R&D.

This position is sponsored by the Roche Postdoctoral Fellowship Programme.

The RPF Programme has the ambition to build and maintain the Scientific Leadership of the future and to provide leading Roche scientists with the opportunity to collaborate with talented postdoctoral researchers, and leading academic research groups, from around the world. One of the key aims is to advance basic science and technologies that will be published in top-rated, peer-reviewed scientific journals, if necessary preceded by priority patent applications.

The duration of the RPF project is initially set for two years, with the possibility of extension for a third year. You will be based in Basel, Switzerland.

Requirements:

You have a Ph.D. degree in cell biology or a related field, with a strong background in kidney health and diseases.You completed your Ph.D. studies not more than 4 years ago.

Furthermore, you also have experience and expertise in the following:

• Mammalian cell culture and primary cell isolation, including podocytes.

• Molecular biology and gene editing techniques.

• High-resolution and high-throughput imaging, data visualization and quantification, advanced statistical analyses

• Scientific writing and presentation skills, documented by publications in high-impact journals or other key contributions.

You have very good interpersonal and communication skills, are able to build good working relationships, and are an outstanding teammate. Your experience and investigative attitude allow you to work independently, to design, perform, and interpret experiments, and to embark on new scientific methodologies.

When does it start?

The planned start of this fellowship is November 2024.

All applications need to include a CV, motivation letter, a publication list and, if available, your PhD certificate.

Do you know what Roche stands for? Roche embraces diversity and equal opportunity in a serious way. We are committed to building a team that represents a variety of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.

If you still have questions, then please check our FAQs and videos on https://careers.roche.com/global/en/ch-faq

More information about the RPF Programme: https://careers.roche.com/global/en/the-roche-postdoctoral-fellowship-programme

Who we are

At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10,700 employees from over 100 countries come together at our Basel/Kaiseraugst site, which is one of Roche`s largest sites. Read more.

Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events.

We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.