Student Intern in Structural Biology

Roche fosters diversity, equity and inclusion, representing the communities we serve. When dealing with healthcare on a global scale, diversity is an essential ingredient to success. We believe that inclusion is key to understanding people’s varied healthcare needs. Together, we embrace individuality and share a passion for exceptional care. Join Roche, where every voice matters.

The Position

We are offering a unique opportunity to join the Structural Biology team in the Roche Innovation Center in Basel .

The Internship is based within Lead Discovery, a part of Roche Pharma Research and Early Development, in collaboration with Antibody and Protein Technologies of Roche Diagnostics. The Structural Biology team delivers cutting-edge structural insights for all research and development across Roche, including small and large molecule research, genomic medicine and diagnostic solution. We are a diverse group of individuals with a broad range of deep expertise in X-ray crystallography, cryo electron microscopy (cryo-EM), protein purification and biophysical methods.

We are looking for a talented master or bachelor student to support the structural biology team in delivering high quality protein structures and insights for our Diagnostics colleagues. The student will have access to world-class X-ray crystallography and cryo-EM facilities. This is a fantastic opportunity for someone who wants to further their practical knowledge in cryo-EM and X-ray crystallography methods while obtaining insights into how these methods are applied in industry.

As an intern you will:

• Be integrated into the Structural Biology team within Lead Discovery

• Work closely in a highly collaborative spirit with Diagnostics colleagues in Germany and USA

• Perform and learn wet-lab experiments on proteins, such as high-throughput crystallisation screening, cryo-EM grid preparation and SPS-PAGE analysis, with the ultimate aim of generating 3D protein structures.

• Use and learn IT tools to solve and build protein structures by X-ray crystallography and/or cryo-EM

• Plan experiments independently and present your results to stakeholders and within group seminars

• Learn how structural biology is a key tool in drug discovery and diagnostics research

We are looking for an inspiring individual who:

• Is dedicated and willing to learn on-the-go, take ownership of projects and has excellent organisational skills.

• Has excellent communication skills and is able to communicate with multiple stakeholders and multi-task projects

• Has a master or a bachelor in biochemistry, biology, biophysics or a related scientific field with a background in structural biology

• Is fluent in English (German is an advantage)

• Has some prior hands-on experience in either X-ray crystallography or cryo-EM (other biophysical methods or protein expression/purification is a plus)

The Internship can starts in September, 2024. Please clearly indicate your preferred starting date in your motivation letter. Applications must include a CV, motivation letter and a certificate of university qualifications

Who we are

At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10,700 employees from over 100 countries come together at our Basel/Kaiseraugst site, which is one of Roche`s largest sites. Read more.

Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events.

We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.