Doctoral Student SNSF in MAPK-induced transcription
Lausanne
Key information
- Publication date:01 September 2025
- Workload:100%
- Place of work:Lausanne
Job summary
Join the University of Lausanne as a Doctoral Student in Microbiology. Enjoy a vibrant campus life with diverse cultures.
Tasks
- Investigate transcription dynamics via MAPK pathways in yeast.
- Utilize live-cell microscopy to study transcription characteristics.
- Conduct wet lab experiments and image analysis for research.
Skills
- Master's degree in Biology or related field; yeast biology experience preferred.
- Fluorescence microscopy and signal transduction knowledge.
- Strong motivation and curiosity for scientific exploration.
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Introduction
The University of Lausanne is a higher teaching and research institution composed of seven faculties with approximately 17’000 students and nearly 4,000 collaborators, professors, and researchers. Ideally situated along the lake of Geneva, near Lausanne's city center, its campus brings together over 120 nationalities.
Presentation
The Department of Fundamental Microbiology ( https://www.unil.ch/dmf ) offers a position of Doctoral Student SNSF focused on transcription dynamics induced by MAPKs. The position is embedded within the quantitative signaling research group of Dr. Serge Pelet (https://wp.unil.ch/quantitativesignaling).
Job information
Expected start date: 01.11.2025
Contract length: 1 year, maximum 4 years
Activity rate: 100%
Workplace: University of Lausanne, Dorigny campus.
Your responsibilities
The aim of the project is to study the dynamics of transcription stimulated by MAPK pathways in the model organism Saccharomyces cerevisiae.
In all eukaryotic cells, MAPK cascades relay extracellular information into a defined biological response, which encompasses the induction of a specific transcriptional program. We have established several live-cell microscopy assays to monitor the dynamics of transcription upon activation of a MAPK pathway in budding yeast. The objective of this project is to apply these tools to understand the role of the promoter sequences in defining the characteristics of the transcription dynamics. In addition, single molecule imaging techniques will be implemented to get deeper insights into the binding of transcription factors on DNA.
The project will combine wet lab experiments, microscopy measurements and image analysis and will provide an excellent scientific training with opportunities for collaborations in a stimulating environment.
Your qualifications
The successful candidate should hold a Master degree in Biology or equivalent, prior experience in yeast biology, signal transduction or fluorescence microscopy is an asset. Candidates without wet lab affinity will not be considered. A good command of the English language, a high personal motivation to excel in science and a curious mind are required.
What the position offers you
We offer a stimulating environment in an international research group. We are part of a multicultural, diversified and dynamic academic environment, with opportunities for professional training. See the lab website ( https://wp.unil.ch/quantitativesignaling) for information on our publications and current research.
Contact for further information
Dr Serge Pelet
Email: E-Mail schreiben
Your application
Deadline : 15.09.2024
Please include your full application (motivation letter, CV with detailed classes and grades, list of publications or presentations, and the contact details of two referees) in a PDF.
Only applications through this website will be taken into account.
Additional information
Seeking to promote an equitable representation of men and women among its staff, the University encourages applications from women.
