Principal Scientist - Computational Chemistry (m/f/d)
myScience
Basel
Key information
- Publication date:05 December 2025
- Workload:100%
- Place of work:Basel
Job summary
Join Syngenta as a Principal Scientist - Computational Chemistry! This role offers a dynamic work environment and great benefits.
Tasks
- Drive innovation in molecular design using computational methods.
- Collaborate with cross-functional teams to optimize molecules.
- Implement AI/ML methodologies to enhance design processes.
Skills
- PhD in computational chemistry or related field required.
- Strong foundation in target- and ligand-based design.
- Proficient in Python and computational chemistry packages.
Is this helpful?
Principal Scientist - Computational Chemistry (m/f/d)
Workplace Basel - North West Switzerland - Switzerland CategoryAgronomy & Food Science | Computer Science
Position Regular Employment / Collaborator
Published 4 December 2025 0
0
Principal Scientist - Computational Chemistry (m/f/d)
Jobs Posts Why us
We are looking for a highly motivated computational chemist to join the Computational Chemistry group at our R&D site in Stein, Switzerland. With strong expertise in computer-aided chemical design and molecular modelling, you will drive innovation in our molecular design processes. As part of your professional development, you will have the opportunity to explore and integrate AI/ML methodologies with traditional computational chemistry approaches to accelerate and improve molecular design of active ingredients. Strong teamwork, excellence in computational design, and the willingness to translate innovative scientific concepts into scalable solutions are essential.
Accountabilities:
Company Description
As a world market leader in crop protection, we help farmers to counter these threats and ensure enough safe, nutritious, affordable food for all - while minimizing the use of land and other agricultural inputs. Syngenta Crop Protection keeps plants safe from planting to harvesting. From the moment a seed is planted through to harvest, crops need to be protected from weeds, insects and diseases as well as droughts and floods, heat and cold. Syngenta Crop Protection is headquartered in Switzerland.
Health Promotion Switzerland recognizes Syngenta’s commitment to the health and well-being of its employees and awards the "Friendly Work Space" label to all its Swiss sites. At Syngenta, employee health and well-being are key to the company.
Qualifications
Required Skills:
Additional Expertise:
Additional Information
Are you interested? Please send your complete application with CV, research summary, diploma and cover letter (if applicable).
Syngenta is an Equal Opportunity Employer and does not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status
Join our talent network
List #1
Latest jobs
Analista de Marketing Operacional Pleno - CROP
Salary
Location
br, Sao Paulo
Job Type
Permanent
Function
Marketing
Remote or Office
On-site
Brand
Syngenta Crop Protection
Location
Sao Paulo
Description
Na Syngenta, nosso objetivo é construir a equipe mais colaborativa e confiável na agricultura, fornecendo sementes de alta qualidade e soluções inovadoras de proteção de cultivos que melhorem o sucess
Reference
e77a2762-47b1-4acc-a295-009366103fd4
Expiry Date
01/01/0001
Read more
Read more
Production Technician 2
Salary
Location
us, Lone Tree
Job Type
Permanent
Function
SE Production Operations
Remote or Office
On-site
Brand
Syngenta Seeds
Location
Lone Tree, IA
Description
Operate equipment and systems in accordance with site specific activities.Drive Forklifts, operate pallet wraps, support systems such as conditioning, packaging, and treating.May assist in managing fi
Reference
ca3d3350-b0d7-44ba-b6e4-04cea0dc0451
Expiry Date
01/01/0001
Read more
Read more
TMD-Manager - Andhra Pradesh
Salary
Location
in, Guntur
Job Type
Permanent
Function
Management / Support
Remote or Office
On-site
Brand
Syngenta Crop Protection
Location
Guntur
Description
Role purposeTo conduct the TMD trials of NPI for getting better clarity about product concept & communication along with creation of the storylines to demonstrate performance of NPIs in market place.T
Reference
455bdeae-ccd3-4b93-bb45-b3052c4407f4
Expiry Date
01/01/0001
Read more
Read more
Representante Técnico de Vendas Sênior - CROP
Salary
Location
br, Querência
Job Type
Permanent
Function
Sales
Remote or Office
On-site
Brand
Syngenta Crop Protection
Location
Querência
Description
Na Syngenta, nosso objetivo é formar uma equipe mais colaborativa e confiável na agricultura, fornecendo sementes de alta qualidade e soluções inovadoras de proteção de cultivos que impulsionam o suce
Reference
220dc6f6-70f3-43fc-b821-d70d68a3e094
Expiry Date
01/01/0001
Read more
Read more
Experimental Seeds Production Technician (w/m/d)
Salary
Location
de, Bad Salzuflen
Job Type
Permanent
Function
Operations & Trialing
Remote or Office
On-site
Brand
Syngenta Seeds
Location
Bad Salzuflen
Description
Die Syngenta Seeds GmbH in Bad Salzuflen sucht zum nächstmöglichen Zeitpunkt eine (n):Experimental Seeds Production Technician (w/m/d)Rollenbeschreibung:Als Experimental Seeds Production Technician si
Reference
2c5f6410-74da-4fef-bd7f-9e4cba13c671
Expiry Date
01/01/0001
Read more
Read more
Site Manager
Salary
Location
us, Lone Tree
Job Type
Permanent
Function
SE Production Operations
Remote or Office
On-site
Brand
Syngenta Seeds
Location
Lone Tree, IA
Description
At Syngenta, our goal is to build the most collaborative and trustworthy team in agriculture, providing top-quality seeds and innovative crop protection solutions that improve farmers’ success. To sup
Reference
541bde8e-1895-46c9-967c-40f017c3c37d
Expiry Date
01/01/0001
Read more
Read more
Representante Técnico de Vendas Especialista - CROP
Salary
Location
br, Lucas do Rio Verde
Job Type
Permanent
Function
Sales
Remote or Office
On-site
Brand
Syngenta Crop Protection
Location
Lucas Do Rio Verde
Description
Na Syngenta, nosso objetivo é construir a equipe mais colaborativa e confiável na agricultura, fornecendo sementes de alta qualidade e soluções inovadoras de proteção de cultivos que melhorem o sucess
Reference
f1d77e04-feb7-441b-9e22-73c825685f54
Expiry Date
01/01/0001
Read more
Read more
Phenotyping Associate Scientist
Salary
Location
ro, Bucharest
Job Type
Permanent
Function
Operations & Trialing
Remote or Office
On-site
Brand
Syngenta Seeds
Location
Bucharest
Description
Role purpose:Support trialing activities by applying agronomic knowledge and data expertise to collect, check and store phenotyping data, contributing to informed decision-making in plant breeding and
Reference
db265bcd-5e17-49e1-8c42-3cb2e04b01e0
Expiry Date
01/01/0001
Read more
Read more
Technical Market Development Officer
Salary
Location
pk, Multan
Job Type
Permanent
Function
Product Biology
Remote or Office
On-site
Brand
Syngenta Crop Protection
Location
Multan
Description
Role PurposeThis role requires technical excellence having good market insight to support commercial & technical development in Pakistan. Develop close liaison with R&D and marketing team to help in p
Reference
6c53994d-aece-48cb-8a26-fec17b3385a0
Expiry Date
01/01/0001
Read more
Read more
Legal Operations Billing Specialist
Salary
Location
hu, Budapest
Job Type
Permanent
Function
Legal Management / Support
Remote or Office
On-site
Brand
Syngenta Group
Location
Budapest
Description
As a Legal Operations Billing Specialist, you will handle day-to-day operational tasks to ensure a smooth and customer oriented end-to-end process for Legal Department invoices across multiple Legal E
Reference
949a8a0a-0e3c-450a-ab1a-36a4cb09b613
Expiry Date
01/01/0001
Read more
Read more
List #1
Articles you might be interested in
An innovation summit in Tel Aviv addresses farming’s global challenges
Teaser
News
Content Type
Blog
Publish date
07/18/2022
Summary
Collaboration and innovation are at the heart of Syngenta Group’s approach to global agriculture. Driven by that spirit, the company recently convened "Innovating Together" in Tel Aviv, a three-day co
Teaser
Collaboration and innovation are at the heart of Syngenta Group’s approach to global agriculture. Driven by that spirit, the company recently convened "Innovating Together" in Tel Aviv, a three-day conference with Israeli innovators and research scientists to exchange insights into ways advanced agriculture can address the global food crisis and climate change.
Read more
My Garden: The grand finale
Teaser
Stories
Content Type
Blog
Publish date
07/15/2022
Summary
The My Garden project started by our Syngenta Group Ambassador comes to its grand finale, with a group of friends enjoying Aleksander’s fresh produce. Over the past few months our Syngenta Group Amba
Teaser
The My Garden project started by our Syngenta Group Ambassador comes to its grand finale, with a group of friends enjoying Aleksander’s fresh produce.
Read more
Tackling the food and climate crises with regenerative agriculture
Teaser
News
Content Type
Blog
Publish date
07/14/2022
Summary
By Syngenta Group News Service May 2022 Syngenta Group CEO Erik Fyrwald calls for wider science-based dialogue on transforming agriculture. In a recent interview with Switzerland’s NZZ am Sonntag, our
Teaser
Syngenta Group CEO Erik Fyrwald calls for wider science-based dialogue on transforming agriculture.
Read more
Syngenta presents Interra® Scan: high-resolution soil mapping for better soil health
Teaser
News
Content Type
Blog
Publish date
07/13/2022
Summary
Licensing agreement with HL Hutchinsons (HLH) signed to supply farmers with precision soil analysis service Interra® Scan offers one of the world’s highest resolution soil mapping services to optimiz
Teaser
Syngenta has signed a licensing agreement with UK based HL Hutchinsons (HLH) to supply agronomists and farmers with an advanced soil mapping and sampling service initially in continental and Eastern Europe.
Read more
Partnering forimpact
Teaser
News
Content Type
Blog
Publish date
07/04/2022
Summary
Syngenta Group is committed to building on our rich network of strategic sustainability partnerships with academic institutions, the food value chain, agricultural businesses and farmers to increase t
Teaser
Syngenta Group is committed to building on our rich network of strategic sustainability partnerships with academic institutions, the food value chain, agricultural businesses and farmers to increase the impact we can make together. We believe that no one business or organization can do enough alone and strongly support Sustainable Development Goal 17, which promotes partnerships between governments, the private sector and civil society.
Read more
We offer very diverse opportunities for leaders, experts, students and graduates. And we will nurture you, so you can grow and contribute in your own unique way.
Search jobs and apply
We offer very diverse opportunities for leaders, experts, students and graduates. And we will nurture you, so you can grow and contribute in your own unique way.
Join our talent network
job
Keyword: No Keyword
Options: 116, 12, 725, 688, 1663
Location: DE
City: Falkenstein
GeoOptions: 297, 1071
0
Principal Scientist - Computational Chemistry (m/f/d)
- __vacancyopjusttionswidget.opt- Brand__ Syngenta Crop Protection
- Location: 4332 Stein
- Function Research Chemistry
This vacancy has expired
This doesn’t mean the journey ends here. Click below to continue your new career path.Jobs Posts Why us
Job description
We are looking for a highly motivated computational chemist to join the Computational Chemistry group at our R&D site in Stein, Switzerland. With strong expertise in computer-aided chemical design and molecular modelling, you will drive innovation in our molecular design processes. As part of your professional development, you will have the opportunity to explore and integrate AI/ML methodologies with traditional computational chemistry approaches to accelerate and improve molecular design of active ingredients. Strong teamwork, excellence in computational design, and the willingness to translate innovative scientific concepts into scalable solutions are essential.
Accountabilities:
- Design and optimize molecules guided by data-driven hypotheses, in partnership with chemists, biologists, and other crop protection scientific experts
- Develop and implement computational workflows to support molecular design
- Create structure-property relationships to guide design decisions
- Explore emerging computational methods to improve the molecular design effectiveness
- Provide systematic feedback to drive continuous improvement of computational chemistry infrastructures, workflows and algorithm implementation
Company Description
As a world market leader in crop protection, we help farmers to counter these threats and ensure enough safe, nutritious, affordable food for all - while minimizing the use of land and other agricultural inputs. Syngenta Crop Protection keeps plants safe from planting to harvesting. From the moment a seed is planted through to harvest, crops need to be protected from weeds, insects and diseases as well as droughts and floods, heat and cold. Syngenta Crop Protection is headquartered in Switzerland.
Health Promotion Switzerland recognizes Syngenta’s commitment to the health and well-being of its employees and awards the "Friendly Work Space" label to all its Swiss sites. At Syngenta, employee health and well-being are key to the company.
Qualifications
Required Skills:
- PhD in computational chemistry or related field
- Strong foundation in target- and ligand-based design
- Proficiency with standard computational chemistry/cheminformatics packages
- Experience with computational workflows (virtual screening, compound library design)
- Working knowledge of Python programming
- Basic understanding of statistics and data analysis
- Proficiency in both Windows and Unix operating systems, including batch/shell scripting and CLI automation
- Demonstrated experience with High-Performance Computing (HPC) and distributed computing environments
- Demonstrated ability to work effectively in cross-functional teams
Additional Expertise:
- Machine learning concepts and their applications in chemistry
- Advanced data analysis and visualization techniques
- Software development
Additional Information
- We provide access to state-of-the-art research facilities and technologies, enabling you to apply and expand your expertise in computational design and active ingredient optimization.
- We cultivate a dynamic and intellectually stimulating working environment, with an open culture and diverse workforce, where new ideas are always welcome. We embrace flexible work arrangements and foster work-life balance.
- We invest in your professional growth and development through a multidisciplinary training program tailored to foster a rewarding career in crop protection. Specifically, we offer comprehensive training and development opportunities to expand your expertise in AI/ML applications for computational chemistry, statistics, programming and software development.
- We are part of a strong regional Science hub, offering you the opportunity to interact with a rich community of scientists in life sciences, further enhancing your professional network and knowledge exchange.
- You will profit from a competitive pension fund plan, attractive bonus system, onsite doctor, fitness room, canteen, and other benefits (Family friendly initiatives, Child and Family allowance...)
Are you interested? Please send your complete application with CV, research summary, diploma and cover letter (if applicable).
Syngenta is an Equal Opportunity Employer and does not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status
Join the most trusted and collaborative team in agriculture
We offer very diverse opportunities for leaders, experts, students and graduates. And we will nurture you, so you can grow and contribute in your own unique way.Join our talent network
List #1
Latest jobs
Analista de Marketing Operacional Pleno - CROP
Salary
Location
br, Sao Paulo
Job Type
Permanent
Function
Marketing
Remote or Office
On-site
Brand
Syngenta Crop Protection
Location
Sao Paulo
Description
Na Syngenta, nosso objetivo é construir a equipe mais colaborativa e confiável na agricultura, fornecendo sementes de alta qualidade e soluções inovadoras de proteção de cultivos que melhorem o sucess
Reference
e77a2762-47b1-4acc-a295-009366103fd4
Expiry Date
01/01/0001
Read more
Read more
Production Technician 2
Salary
Location
us, Lone Tree
Job Type
Permanent
Function
SE Production Operations
Remote or Office
On-site
Brand
Syngenta Seeds
Location
Lone Tree, IA
Description
Operate equipment and systems in accordance with site specific activities.Drive Forklifts, operate pallet wraps, support systems such as conditioning, packaging, and treating.May assist in managing fi
Reference
ca3d3350-b0d7-44ba-b6e4-04cea0dc0451
Expiry Date
01/01/0001
Read more
Read more
TMD-Manager - Andhra Pradesh
Salary
Location
in, Guntur
Job Type
Permanent
Function
Management / Support
Remote or Office
On-site
Brand
Syngenta Crop Protection
Location
Guntur
Description
Role purposeTo conduct the TMD trials of NPI for getting better clarity about product concept & communication along with creation of the storylines to demonstrate performance of NPIs in market place.T
Reference
455bdeae-ccd3-4b93-bb45-b3052c4407f4
Expiry Date
01/01/0001
Read more
Read more
Representante Técnico de Vendas Sênior - CROP
Salary
Location
br, Querência
Job Type
Permanent
Function
Sales
Remote or Office
On-site
Brand
Syngenta Crop Protection
Location
Querência
Description
Na Syngenta, nosso objetivo é formar uma equipe mais colaborativa e confiável na agricultura, fornecendo sementes de alta qualidade e soluções inovadoras de proteção de cultivos que impulsionam o suce
Reference
220dc6f6-70f3-43fc-b821-d70d68a3e094
Expiry Date
01/01/0001
Read more
Read more
Experimental Seeds Production Technician (w/m/d)
Salary
Location
de, Bad Salzuflen
Job Type
Permanent
Function
Operations & Trialing
Remote or Office
On-site
Brand
Syngenta Seeds
Location
Bad Salzuflen
Description
Die Syngenta Seeds GmbH in Bad Salzuflen sucht zum nächstmöglichen Zeitpunkt eine (n):Experimental Seeds Production Technician (w/m/d)Rollenbeschreibung:Als Experimental Seeds Production Technician si
Reference
2c5f6410-74da-4fef-bd7f-9e4cba13c671
Expiry Date
01/01/0001
Read more
Read more
Site Manager
Salary
Location
us, Lone Tree
Job Type
Permanent
Function
SE Production Operations
Remote or Office
On-site
Brand
Syngenta Seeds
Location
Lone Tree, IA
Description
At Syngenta, our goal is to build the most collaborative and trustworthy team in agriculture, providing top-quality seeds and innovative crop protection solutions that improve farmers’ success. To sup
Reference
541bde8e-1895-46c9-967c-40f017c3c37d
Expiry Date
01/01/0001
Read more
Read more
Representante Técnico de Vendas Especialista - CROP
Salary
Location
br, Lucas do Rio Verde
Job Type
Permanent
Function
Sales
Remote or Office
On-site
Brand
Syngenta Crop Protection
Location
Lucas Do Rio Verde
Description
Na Syngenta, nosso objetivo é construir a equipe mais colaborativa e confiável na agricultura, fornecendo sementes de alta qualidade e soluções inovadoras de proteção de cultivos que melhorem o sucess
Reference
f1d77e04-feb7-441b-9e22-73c825685f54
Expiry Date
01/01/0001
Read more
Read more
Phenotyping Associate Scientist
Salary
Location
ro, Bucharest
Job Type
Permanent
Function
Operations & Trialing
Remote or Office
On-site
Brand
Syngenta Seeds
Location
Bucharest
Description
Role purpose:Support trialing activities by applying agronomic knowledge and data expertise to collect, check and store phenotyping data, contributing to informed decision-making in plant breeding and
Reference
db265bcd-5e17-49e1-8c42-3cb2e04b01e0
Expiry Date
01/01/0001
Read more
Read more
Technical Market Development Officer
Salary
Location
pk, Multan
Job Type
Permanent
Function
Product Biology
Remote or Office
On-site
Brand
Syngenta Crop Protection
Location
Multan
Description
Role PurposeThis role requires technical excellence having good market insight to support commercial & technical development in Pakistan. Develop close liaison with R&D and marketing team to help in p
Reference
6c53994d-aece-48cb-8a26-fec17b3385a0
Expiry Date
01/01/0001
Read more
Read more
Legal Operations Billing Specialist
Salary
Location
hu, Budapest
Job Type
Permanent
Function
Legal Management / Support
Remote or Office
On-site
Brand
Syngenta Group
Location
Budapest
Description
As a Legal Operations Billing Specialist, you will handle day-to-day operational tasks to ensure a smooth and customer oriented end-to-end process for Legal Department invoices across multiple Legal E
Reference
949a8a0a-0e3c-450a-ab1a-36a4cb09b613
Expiry Date
01/01/0001
Read more
Read more
List #1
Articles you might be interested in
An innovation summit in Tel Aviv addresses farming’s global challenges
Teaser
News
Content Type
Blog
Publish date
07/18/2022
Summary
Collaboration and innovation are at the heart of Syngenta Group’s approach to global agriculture. Driven by that spirit, the company recently convened "Innovating Together" in Tel Aviv, a three-day co
Teaser
Collaboration and innovation are at the heart of Syngenta Group’s approach to global agriculture. Driven by that spirit, the company recently convened "Innovating Together" in Tel Aviv, a three-day conference with Israeli innovators and research scientists to exchange insights into ways advanced agriculture can address the global food crisis and climate change.
Read more
My Garden: The grand finale
Teaser
Stories
Content Type
Blog
Publish date
07/15/2022
Summary
The My Garden project started by our Syngenta Group Ambassador comes to its grand finale, with a group of friends enjoying Aleksander’s fresh produce. Over the past few months our Syngenta Group Amba
Teaser
The My Garden project started by our Syngenta Group Ambassador comes to its grand finale, with a group of friends enjoying Aleksander’s fresh produce.
Read more
Tackling the food and climate crises with regenerative agriculture
Teaser
News
Content Type
Blog
Publish date
07/14/2022
Summary
By Syngenta Group News Service May 2022 Syngenta Group CEO Erik Fyrwald calls for wider science-based dialogue on transforming agriculture. In a recent interview with Switzerland’s NZZ am Sonntag, our
Teaser
Syngenta Group CEO Erik Fyrwald calls for wider science-based dialogue on transforming agriculture.
Read more
Syngenta presents Interra® Scan: high-resolution soil mapping for better soil health
Teaser
News
Content Type
Blog
Publish date
07/13/2022
Summary
Licensing agreement with HL Hutchinsons (HLH) signed to supply farmers with precision soil analysis service Interra® Scan offers one of the world’s highest resolution soil mapping services to optimiz
Teaser
Syngenta has signed a licensing agreement with UK based HL Hutchinsons (HLH) to supply agronomists and farmers with an advanced soil mapping and sampling service initially in continental and Eastern Europe.
Read more
Partnering forimpact
Teaser
News
Content Type
Blog
Publish date
07/04/2022
Summary
Syngenta Group is committed to building on our rich network of strategic sustainability partnerships with academic institutions, the food value chain, agricultural businesses and farmers to increase t
Teaser
Syngenta Group is committed to building on our rich network of strategic sustainability partnerships with academic institutions, the food value chain, agricultural businesses and farmers to increase the impact we can make together. We believe that no one business or organization can do enough alone and strongly support Sustainable Development Goal 17, which promotes partnerships between governments, the private sector and civil society.
Read more
Start your job search now
Every one of our talented employees helps shape who we are and the impact we make on agriculture.We offer very diverse opportunities for leaders, experts, students and graduates. And we will nurture you, so you can grow and contribute in your own unique way.
Search jobs and apply
Join the most trusted and collaborative team in agriculture
Every one of our talented employees helps shape who we are and the impact we make on agriculture.We offer very diverse opportunities for leaders, experts, students and graduates. And we will nurture you, so you can grow and contribute in your own unique way.
Join our talent network
- Location: 4332 Stein
job
Keyword: No Keyword
Options: 116, 12, 725, 688, 1663
Location: DE
City: Falkenstein
GeoOptions: 297, 1071
In your application, please refer to myScience.ch and referenceJobID68860.
