Lab Technician - Cell culture & purification

The Technology & Innovation department strives to transform Global Drug Substance Development (GDSD) operations by exploring and evaluating cutting-edge technologies with agility and efficiency. Our mission is to create a diverse project portfolio that ranges from quick wins to visionary advancements and shine a light on future trends and empower our teams to embrace every challenge as an opportunity for growth.

Key Responsibilities

This position is permanent and full-time, and to start immediately.

Upstream Processing (USP)

• Perform cell culture experiments using suspension-adapted mammalian cell lines (CHO) following established experimental procedures in deep well plates, shake flasks, wave-bags and bioreactors operated in perfusion mode.
• Conduct routine monitoring of bioreactors as required by the USP process.

Downstream Processing (DSP)

· Purify cell culture harvest using membrane/chromatography, and TFF facilities.

Experimentation & Data Management

• Organisation of experimental pre-requisites- ordering buffer, media, feeds, consumables for laboratory activities
• Conduct and assist in laboratory experiments, ensuring proper collection, analysis, and documentation of raw data.
• Monitor and support the progress of laboratory activities related to specific projects

Equipment Operation & Maintenance

• Participate as department representative for common lab activities, troubleshooting, organizational improvements, coordination of equipment calibration and/or maintenance.
• Ensure proper management of laboratory stocks, including equipment and consumables.

Desired Skills & Expertise

• Hands-on experience in mammalian cell culture (aseptic handling techniques), including bioreactor operation.
• Experience in AKTA and TFF systems.
• Understanding of laboratory automation tools
• Ability to work effectively in a collaborative, fast-paced laboratory environment.

Soft skills

• Ensure proper training of interns.
• Scientifically curious, proactive, willingness to learn;
• Detail-oriented with strong problem-solving abilities.
• Hands-on approach
• with a high level of rigor, discipline, and precision.
• Self-motivated and capable of working independently, while effectively collaborating within a multicultural team.
• Flexibility and adaptability in a fast-paced and dynamic environment.

Educational and Experience

• Technician's diploma, Bachelor's, or equivalent (CFC, HES, BTS, IUT) in biochemistry, biology, or a related field.
• Minimum of 1 year of experience in pharmaceutical production, specifically in clinical or commercial USP.

Language and IT Skills

• Ability to communicate in both French and English.
• Microsoft Office- Excel, Word, Powerpoint.