Biomedical Research Officer (Postdoctoral Researcher)

About the job

Research

Research Officer at the Institute of Pathology

The Institute of Pathology at CHUV is seeking a biomedical research officer (postdoctoral researcher) at a workload of 80% to 100% within the framework of the TANDEM project. The position is offered on a fixed-term contract of one year, renewable, starting 1 December 2026.

Context

The Lausanne University Hospital (CHUV) is one of the five Swiss university hospitals. Thanks to its collaboration with the Faculty of Biology and Medicine of the University of Lausanne and EPFL, CHUV plays a leading role in medical care, medical research, and education.

The Institute of Pathology brings together diagnostic and research laboratories. The group of Prof. Laurence de Leval, specialised in lymphomas, is conducting with the Biomedical Data Science Center (Prof. Raphael Gottardo) a TANDEM project funded by the ISREC Foundation: "Digital Pathology Meets Spatial Proteomics: Transforming Precision Diagnosis of T-cell Lymphoma".

This project aims to improve the diagnosis of peripheral T-cell lymphomas by combining spatial proteomics and transcriptomics, single-cell sequencing, digital pathology, and artificial intelligence. It notably relies on cyclic immunofluorescence (COMET™, Lunaphore), H&E imaging, and Visium HD technology, in collaboration with teams from CHUV, UNIL, and LYSA (France).

Mission

• You ensure the scientific management and monitoring of the TANDEM project in collaboration with the two principal co-investigators
• You develop and validate standard operating procedures (SOPs) for multiplex imaging and spatial profiling, and coordinate the production of quality data
• You perform image processing and quantitative analysis of spatial proteomics data
• You contribute to the development of a computational pathology pipeline combining H&E imaging, spatial proteomics data, and machine learning
• You participate in the training and evaluation of generative AI models to predict multiplex markers from H&E images
• You develop reproducible multi-omics data analyses and contribute to the identification of biomarkers and biological mechanisms
• You ensure documentation, quality, and reproducibility of analyses and collaborate with clinical, scientific, and data science teams
• You participate in the dissemination of results through reports, presentations, and scientific publications.

Profile

• You hold a doctorate (PhD) in biomedical sciences or data sciences
• You have experience in spatial biology, pathology, or complex biological data analysis, ideally multi-omics or single-cell
• You master histological analyses, immunohistochemistry, and multiplex immunofluorescence and have experience in interdisciplinary project management
• You possess strong skills in applied statistics for life sciences (linear models, generalized models, multivariate and association analyses)
• You are proficient in R and/or Python for data analysis and bioinformatics tool development
• You show a strong interest in fundamental, translational, and clinical research as well as innovative data-driven approaches
• You demonstrate autonomy, initiative, creativity, and rigour and have excellent collaboration, organisation, and scientific communication skills

Depending on your profile, the salary class will be between levels 10 and 11 and the job description may be adapted.

We offer

Becoming a collaborator at the Lausanne University Hospital means benefiting from:

• First-class social benefits, 20 days paternity leave, and 4 months maternity leave (with the possibility of an additional month of breastfeeding leave)
• Regular salary progression adapted to responsibilities
• A 13th salary and 25 days of holiday per year
• A right to a minimum of three training days per year, with access to a varied offer within the CHUV Training Centre and partner training centres of the State of Vaud
• Facilitated access to one of the 500 furnished accommodations offered in the surrounding neighbourhoods for people relocating to Switzerland from abroad
• Social, cultural, and economic benefits offered to members of the H-Oxygène association
• Benefits offered within the mobility plan (discounts on public transport subscriptions, promotion of "Mobility" vehicles, and discounts on the purchase of electric bicycles)
• Hotel-quality staff restaurants in each hospital building with preferential rates.

Contact and application submission

Contact for information about the position: Prof. Laurence de Leval at 021 314 71 94, Prof. Raphaël Gottardo at 079 556 23 08 or Mr Roberto Colotti at 079 556 92 71.

As all our applications are processed electronically, we kindly ask you to apply exclusively online by clicking the APPLY button at the bottom of the announcement.

If you have difficulty applying, you can consult our procedure on how to apply online. If for technical reasons you cannot apply online, we invite you to contact our Recruitment Unit, which will assist you in your process, either by email at e.recrutement@chuv.ch or by phone at 021 314 85 70.

CHUV applies the highest quality standards in its recruitment processes. Furthermore, committed to promoting diversity among our collaborators, we pay attention to different life paths and do everything possible to ensure equal treatment and avoid any discrimination. We look forward to receiving your application.

We kindly ask placement agencies to note that applications submitted directly by them on our recruitment platform are not accepted and cannot be invoiced. Thank you for your understanding.