Studentische Hilfsassistenz - PK/PD Models 20 %
Universität Bern
Key information
- Publication date:10 July 2025
- Workload:20%
- Place of work:Bern
Job summary
Join the University of Bern's PrecisionLab, which is dedicated to diabetes innovation. This role offers a unique opportunity in a dynamic research environment.
Tasks
- Identify mathematical models for pharmacokinetics of incretin medications.
- Review literature on physiological mechanisms of action for medications.
- Test proposed mathematical structures in simulations and analyze data.
Skills
- Must have a Master in pharmacy, biomedical engineering, or related field.
- Experience in PK/PD modeling of drugs or biomarkers is essential.
- Proficient in programming languages like Matlab or Python.
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University of Bern and University Hospital Bern, Department of Diabetes, Endocrinology, Nutritional Medicine and Metabolism (UDEM)
Start of employment: By arrangement
Employment: limited term of three years - after three years, depending on further funding.
PrecisionLab, led by Prof. Jose Garcia-Tirado, aims to develop new technology for managing diabetes and metabolic disorders through novel digital interventions such as advanced decision-support tools and automated insulin delivery.
Job purpose and responsibilities
You work primarily on identifying the mathematical structure and parameters of a compartmental model describing the pharmacokinetic (PK)/pharmacodynamic (PD) of novel incretin medications used for glucose control and body weight reduction in people with type 2 diabetes. Specifically:
- Review the literature to understand the physiology mechanisms of action of these medications
- Propose different mathematical structures describing the PK of a selected medication candidate and test them in simulation
- Carry out the identification of the model parameter distributions using data from the literature
Requirements
A Must:
- Master student in pharmacy, biomedical engineering, or a close field
- Previous experience in identifying PK/PD models for drugs or biomarkers
- Previous experience in computer programming (Matlab, Python, or similar)
We offer
- We provide excellent scientific expertise in a dynamic environment and support a career focusing on translational research
- A workplace in Bern, Switzerland's capital, known for its high quality of life and surrounded by beautiful nature, perfect for hiking, biking, swimming, and winter sports
Application and contact
For subject-specific questions and information about the position, please contact E-Mail schreiben.
