Research Scientist / Senior Scientist – Protein Sciences (Novartis Biomedical Research)

Responsibilities

You will work to produce high-quality proteins for drug discovery, focusing on small molecule hit generation, validation, and structural biology. Key responsibilities include:

• Express proteins insect and mammalian cell culture systems.
• Purify proteins using chromatography techniques and FPLC equipment to enable downstream assays and structural biology for drug discovery.
• Collaborate with team members to enable cryo-EM structural characterization of membrane proteins.
• Optimize protocols and processes through literature research, ideation and hands-on wet lab exploration.
• Work closely in a matrix setting with lab associates and present findings to project teams.
   

Minimum Requirements

• Completed apprenticeship as a laboratory technician with 2 years of practical work experience or Bachelor/Masters in biochemistry, biology, molecular biology, life sciences, or a related field with strong experience in wet lab work.
• In-depth theoretical knowledge and hands-on experience in protein biochemistry, including expression, purification, and characterization.
• Strong collaboration, organizational, and communication skills in oral and written English, with the ability to effectively present results in team settings.
• Proactive interest in acquiring new techniques in protein biochemistry, biophysics, and structural biology.
   

Desirable Requirements

• Hands-on experience in membrane protein expression, purification, characterization, and familiarity with cryo-EM workflows (sample preparation, grid handling).
• Prior exposure to an industrial research environment.
• Familiarity with software tools for structural analysis and AI driven protein construct design (PyMol, AlphaFold, etc.).

Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture

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